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GLP-1 medications carry a theoretical risk of pancreatitis (inflammation of the pancreas), and patients without gallbladders may have slightly elevated baseline pancreatic stress if they had gallstones or biliary issues before surgery

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J Alzheimers Dis 29:783791 Couch JA, Yu YJ, Zhang Y, Tarrant JM, Fuji RN, Meilandt WJ, Solanoy H, Tong RK, Hoyte K, Luk W (2013) Addressing safety liabilities of TfR bispecific antibodies that cross the blood-brain barrier