Eating smaller, more frequent meals and avoiding rich or greasy foods can help reduce discomfort
Int J Biochem Cell Biol 42(9): 13769
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If symptoms are particularly troublesome, your doctor may recommend: Slower dose escalation than standard protocols Temporary dose reduction Switching to a different GLP-1 agonist, as individual responses vary Short-term use of anti-diarrhoeal medications such as loperamide for acute episodes, though this should only be done under medical supervision and avoided if you have blood in your stool, fever, or suspected infection If you're also taking insulin or sulfonylureas, monitor your blood glucose more frequently during periods of reduced appetite or diarrhoea, as you may need dose adjustments to prevent hypoglycaemia
Liraglutide's protective effect was further verified in the anterior cruciate ligament (ACL) rat model, in which sub-cutaneous injection of liraglutide 50 g/kg/day for 3 or 6 weeks decreased the number of caspase 3- and CHOP-positive cells in cartilage [35]
