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This led researchers to investigate liraglutide as a stand-alone treatment for obesity
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Among all the active GLP-1R structures, H363 6.52b dipped into the TMD core whereas it is reoriented ~90 to an outside-facing position and formed a hydrogen bond with Q394 7.49b through dismissal of the hydrogen bond with the backbone carbonyl oxygen atom of P358 6.47b
Additionally, for patients with type 2 diabetes, Ozempic improves glycemic control by helping to stabilize blood sugar levels and reduce the risk of cardiovascular complications
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