UF Health Cancer Center shared a post on LinkedIn: A new study by University of Florida researchers and collaborators has found that a popular class of weight loss drugs is associated with lower cancer risk
Drug-specific monitoring schedule | Drug | Monitoring parameter | Timing after GLP-1 start | |---|---|---| | Warfarin | INR | 2 weeks, 4 weeks, then per standard | | Levothyroxine | TSH | 6 to 8 weeks | | Cyclosporine/tacrolimus | Trough level | Weekly for first 8 weeks | | Oral contraceptive | Add barrier method | For first 4+ weeks per Ozempic label | | Digoxin | Serum digoxin, ECG if symptomatic | 4 weeks | | Lithium | Serum lithium | 2 to 4 weeks, especially if nausea reduces fluid intake | What the Clinical Trial Data Actually Show Most large GLP-1 outcome trials were not designed to measure drug-drug interactions, but pharmacokinetic sub-studies and post-marketing data fill some gaps
They set up a policy where compounders could work around FDA approval guidelines in cases of shortages. But right now, there is no shortage of GLP-1 medications, and because companies like Eli Lilly and Novo Nordisk have patents, patients are likely years away from FDA-approved generics
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PMID: 122 BalaliASadeghiOKhorvashFRouhaniMHAskariG
