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Some of the names I discussed in that primer have done pretty well - AIRS is up 70% since that piece, and overall basket is up 17% since then

While preclinical or earlier-stage trials in selected populations might still explore the potential of GLP-1 receptor agonists in neurodegeneration, these results serve as a reality check

DZ: Supervision, Writing review & editing

But commodity, non-integrated products like Ibuprofen (where Chinese competition is fierce and cost structures are unfavorable) destroy value

It is shallow, so the needle only travels a short distance, and it has fewer pain-sensitive nerves than deeper tissue, so most people feel a small pinch rather than a deep ache