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Studies of Rho proteins in other brain cells, including astrocytes and microglia, are also of importance in understanding the role of Rho signaling in synaptic regulation

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MOTS-c activates AMPK (AMP-activated protein kinase), the master metabolic switch that signals cells to increase glucose uptake, accelerate fat oxidation, and promote mitochondrial biogenesis

While current treatment options for alcohol use disorder and depression exist, there is a need for more targeted strategies that address the underlying neurobiological mechanisms contributing to ethanol-induced depression

BPC-157 is a synthetic peptide derived from a protein found in gastric juice