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Activation of these brain regions by leptin is partly attributable to its actions on ARC neurons which lie outside of the blood-brain barrier

Animal and laboratory studies have produced promising findings related to tissue repair, tendon healing, ligament recovery and gastrointestinal protection

[DOI] [PubMed] [Google Scholar] 87.Ma L., Dou H.L., Huang Y.M., Huang Y.M., Lu X.R., Xu X.R., Qian F., Zou Z.Y., Pang L.H., Dong P.C., et al

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Similarly, endothelium-mediated vasodilator responses were restored when a transgene for GPx1 was introduced into the CBS +/ mice by crossbreeding transgenic GPx1 overexpressing mice and CBS deficient mice, suggesting that increased expression of GPx1 could compensate for the negative effects of homocysteine on bioactive NO [60]