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The inducers are: (1) ACSL4, as a major regulator in the pathophysiology of ferroptosis, which stimulates it by increasing the content of long PUFAs and omega-6 PUFAs in the cell membrane ( Research Progress Into Ferroptosis in Ophthalmology The clinical application of ferroptosis is currently mainly being studied in terms of nervous system diseases, tumors, and ischemia/reperfusion injury

Sources Eyth, E., Zubair, M., & Naik, R

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