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This is why burst C rating can easily create false confidence when it is read in isolation

These medications are ideal for patients who have struggled with weight loss through diet and exercise alone and need medical support to achieve lasting success

Such patterns contribute to relapse vulnerability and poorer long-term outcomes, as difficulties in emotion regulation are robustly linked to weight regain [14], and emotional eating mediates adverse body mass index (BMI) trajectories and worsened mental health outcomes [15]

Numerous clinical trials are exploring the therapeutic roles of glucagon-like peptide (GLP)-1 modulators, insulin-sensitizing thiazolidinediones, and sodium-glucose cotransporter 2 (SGLT2) inhibitors in patients with MASLD, which will be discussed in this section