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La identificacin de la DPP4 como la enzima responsable de la vida media corta de las incretinas llev a plantear que la inhibicin de su accin, podra tener un rol en la terapia de la DM2, al aumentar los niveles de GLP1 y prolongar su accin insulinotrpica47

This means that, overall, tirzepatide is a more effective medication, but can cause more severe side effects, possibly to it being more potent due to its dual-action mechanism

This is great news for people with Type 2 diabetes

The most important distinction: Zepbound is a weight-management medication

Interestingly, new research published in the journal Nature Medicine evaluated the health outcomes of more than 2 million veterans with diabetes taking a GLP-1 and found that while the medications had positive effects on several health conditions, like heart disease and substance use disorders, they were negatively associated with some, including arthritis