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Immune cells contribute to myelin degeneration and axonopathic changes in mice overexpressing proteolipid protein in oligodendrocytes

Growth hormone overexpression in the central nervous system results in hyperphagia-induced obesity associated with insulin resistance and dyslipidemia

Cela permettra aux patients prsentant des problmes dabsorption et ncessitant une administration par injection intramusculaire davoir accs leur traitement

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Perfil de seguridad En los ensayos clnicos de fase II, el AOD-9604 mostr un perfil de tolerabilidad favorable, sin los eventos adversos metablicos caractersticos de la hormona de crecimiento: en particular, no se observ elevacin de la glucemia, resistencia a la insulina ni incremento de IGF-1, lo que constituye su principal diferencia de seguridad frente a la hGH completa