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MuraliManohar, S

Conventional copper-modulating therapies, including chelators (e.g., TTM and TETA) and the ionophore elesclomol, are fundamentally limited by their lack of specificity, which constrains their clinical utility and leads to significant adverse effects

It specifically binds to BAFF (TNFSF13B), promoting the survival and activation of mature B-cells (134)

Cytosolic ALDH1L1 mainly regulates reduced folate pools and purine biosynthesis, while mitochondrial ALDH1L2 produces NADPH in response to oxidative stress

A healthy immune system is better at managing inflammation, which can otherwise lead to redness or an uneven skin tone