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In patients with painful DPN, clinicians should offer tricyclic antidepressants, serotonin-norepinephrine reuptake inhibitors, gabapentinoids and/or sodium channel blockers to reduce pain (Level B) and consider factors other than efficacy (Level B)
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2,8 In addition, if the patient has GI symptoms, including nausea, vomiting, retching, bloating, or abdominal pain, elective surgeries should be delayed