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In contrast to the inhibition of glutaminolysis, pharmacological or genetic targeting of GLUL in macrophages reprograms M2-polarized macrophages to an M1-polarized phenotype 143

Hence, this autoantibody presence especially targets the autonomic and central nervous systems (503), which may explain the dysautonomia and immune dysregulation present in ME/CFS ( In other autoimmune diseases, natural antibodies are found against adrenergic, muscarinergic, and other G protein coupled receptors (GPCR) (512)

Stability of iron complexes in the presence of GSSG The negative ionization mode mass spectrum for complex 1 after 1 min of incubation with GSSG showed two signals at m/z = 229 and at m/z = 611, corresponding to ferrocenecarboxylic acid and the GSSG molecule