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Funding This study was funded by Zambon S.p.A., Italy

While some have modest metabolic support data, none demonstrate the receptor-binding specificity or clinical outcomes of FDA-approved GLP-1 agonists

Human primary small-airway epithelial cells (ATCC, PCS-301-010) were cultured with airway epithelial cell basal medium, according to the manufacturers protocol

Animal studies show restored pineal signaling, and circadian rhythms of melatonin and cortisol improve in aging subjects, supporting its geroprotective profile in preclinical studies

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