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[15] [16] Clinical studies examining the effects of GLP-1 receptor agonists on resting metabolic rate (RMR) and total energy expenditure have produced consistent findings: these medications do not significantly increase metabolic rate

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Some observational studies have noted that patients with type 2 diabetes and rheumatoid arthritis who were treated with GLP-1 agonists experienced modest reductions in inflammatory markers compared to those on other glucose-lowering therapies