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[DOI] [PMC free article] [PubMed] [Google Scholar] Federico A, Morgillo F, Tuccillo C, Ciardiello F, Loguercio C

Its efficacy stems from the modulation of multiple signaling pathways related to oxidative stress and cell survival

The robust presence of innate immune elements at the leading edges led some to conclude that in these chronic active MS lesions, there is a switch with the innate rather than the adaptive immune system taking over to propagate the pathology (Weiner, 2008)