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Then came the SOUL trial , which demonstrated that oral semaglutide also reduces MACE by 14% , establishing that the route of administration does not blunt the cardiovascular protection

This is universal

They contain the same active drug molecules, but the final products can differ in formulation, concentration, and quality

So it was a kind of off-target observation when it was used for individuals with diabetes to then start studying it for obesity

Second, in addition to medullary thyroid carcinoma and C-cell hyperplasia, the expression of GLP-1 receptors in papillary thyroid carcinoma (PTC) has been demonstrated