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Patients with type 2 diabetes do not produce enough GLP-1 on their own, and Januvia allows these hormones to stay active in the blood longer to lower blood sugar levels

One such example is glucagon-like peptide 1 (GLP-1) (3.3 kDa), a small peptide hormone with a plasma half-life of only two minutes due to enzymatic degradation by dipeptidyl peptidase-4 (DDP-4) in the blood and rapid excretion through the kidneys 16,17,18,19

Simultaneously, these agents suppress glucagon secretion from pancreatic alpha cells, further helping to lower blood glucose levels

These include: Bloating and gas : Increased bacterial fermentation produces gases, causing abdominal distension and flatulence Mild abdominal discomfort or cramping : Usually resolves as the microbiome stabilises Changes in bowel habits : Temporary loose stools or, less commonly, constipation Nausea : Occasionally reported, particularly if taken on an empty stomach These symptoms typically diminish within 23 weeks of consistent use

Another way to reduce surface tension is to shear it with a blender or similar mechanical means