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337 Although all cell types responded to this inhibitor in vitro and showed promising therapeutic effects in vivo, 337 phase I clinical trials for treating advanced solid tumors ultimately failed due to cardiovascular toxicity and wide variability in patient responses

Spray 3 sprays under the tongue 2 times a day before meals in the morning and afternoon for 20 days

The main isoforms studied in these PKC studies were prkca and prkce (primarily expressed in cardiac tissue), with less emphasis on prkcg (Manji et al., 1999)

The page is oriented around comparison and decision support and the specifics of cost and coverage, dosing

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