Approximately 20-25% of mCRPC cases display molecular alterations causing homologous recombination deficiency (HRD), such as BRCA1/2 or ATM mutations 33
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The significance of the differences between controls and examined groups were calculated depending on whether the data met the assumptions of normality and variance homogeneity, either using the Students t-test (for data meeting the criteria of normal distribution) or the two-tailed MannWhitney U test (for data without normal distribution)
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