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These effects are inspiring for the possibly therapeutic application of GLP-1 RAs in neurological and cardiovascular complications of diabetes

Jan 2015;39(1):124-128

They have emerged as key therapeutic targets in diabetes and obesity research , ranging from GLP-1 analogs like Semaglutide (Ozempic/Wegovy) to dual and triple agonists (Retatrutide) that synergistically enhance glycemic control and promote weight loss

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These compounds are designed to interact simultaneously with various binding sites on the enzyme