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This decline correlates with reduced tissue regeneration capacity.[2][3] Structurally, GHK-Cu features a Cu(II) ion coordinated in a distorted square-planar pyramid by four nitrogen atoms: the amino-N of glycine, the amide-N of the Gly-His peptide bond, the imidazole-N of histidine, and an oxygen from water or a carboxyl group

Specifically, Asp 21P forms a salt bridge with R242 ECL1 , while Trp 25P forms a hydrogen bond with D244 ECL1 and pi-pi stacking with W249 ECL1 , which was stabilized by Phe 22P

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"The role of endometrial stem cells in the pathogenesis of endometriosis and their application to its early diagnosis"