appeals for gip glp 1 How May Enhance the Therapeutic Efficacy of GLP-1? GIP and GLP-1: similarities and

Leveraging the University of California Health Data Warehouse enabled a realworld analysis of 6,871 patients with primary colon cancer and rigorous adjustment strategies to probe whether GLP1 RA exposure relates to fiveyear mortality. At the end of the study, researchers found that participants with colon cancer taking GLP-1 medications had a 15.5% mortality risk within 5 years, compared to 37.1% in participants not taking the drugs

One contributing factor may be the substantial differences in drug metabolism between rodents and humans

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Future studies should investigate liver enzymes and metabolites in NASH patients treated with L-carnitine, which could help elucidate the mechanism through which L-carnitine can prove beneficial toliver function and provide insights into novel therapeutics.

Front Endocrinol (Lausanne) 2012;3:141