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In an antigen-induced arthritis (AIA) rat model, the administration of AMSP-30m, a HIF-1 inhibitor, was observed to elicit a marked reduction in foot swelling, arthritis index, and histopathological scores, alongside a notable decrease in the serum and synovial tissue levels of inflammatory cytokines, including IL-1, IL-6, and TNF-

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Li Y-J, Fahrmann JF, Aftabizadeh M, Zhao Q, Tripathi SC, Zhang C, et al

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