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This can be an important consideration as one could argue that patients taking GLP-1RAs might differ, compared with patients not on these medications, in their likelihood to have seen an eye care clinician. The commentary encouraged others to take a critical look at the designs and database limitations to understand how confounding, bias and chance may explain discrepancies in studies that rely on large databases

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In the course of studying structure-activity relationships, we obtained the cocrystal structure of inhibitor 16 and Schistosoma japonicum glutathione S-transferase (SjGST, PDB: 8GYD)

This extensive anatomical integration results in substantial overlap between GLP-1 signaling pathways and the mesolimbic dopamine system, which is central to reward-related behaviors

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