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Following this pattern, TMEV-infected SJL/J mice treated orally with this same antibiotic mixture showed protection against motor dysfunction, axonal damage, and CNS immune infiltration, likely through enhanced CD4 + CD39 + T cells, CD5 + CD1d + B cells, and downregulated IL-17 in the periphery (Mestre et al., 2019)

The body doesnt have to convert methylcobalamin into another active form, unlike cyanocobalamin, which is commonly found in oral supplements

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Research is ongoing into biomarkers that specifically indicate peptide use versus natural variation