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In clinical trials, tirzepatide demonstrated average weight loss of up to 22.5% of body weight, exceeding the 15% typically seen with semaglutide at maximum doses
Clinical trials may differ in patient population, baseline weight and BMI, diabetes status, medication dose, treatment duration, nutrition and lifestyle support, dropout rates, side-effect profiles, study design, and whether the data are published, peer-reviewed, or topline results
[DOI] [PubMed] [Google Scholar] Handgraaf S., Dusaulcy R., Visentin F., Philippe J., Gosmain Y
These alternatives are FDA-approved medications designed specifically for chronic weight management