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Exclusion criteria included (a) clinical studies that had menopause hormone therapy as a treatment, (b) case reports, (c) in vitro studies or (d) animal studies, and (e) duplicate articles or off-topic articles
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Moreover, nonsteroidal anti-inflammatory drugs (NSAIDs), prototypic inhibitors of cyclooxygenase (COX) activity and PGE2 production, can trigger or worsen the disease (51, 52)
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