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Semaglutide# Semaglutide has the most extensive GLP-1 evidence base: SUSTAIN (T2D injectable, 7 trials), PIONEER (T2D oral, 9 trials), STEP (obesity, multiple trials), and SELECT (cardiovascular outcomes, n=17,604, 20% MACE reduction)

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Yet instead of CV risk, the strongest factors associated with the use of these novel diabetes medications were elevated HbA1c and younger patient age. Researchers collected data from 68,126 adults with type 2 diabetes hospitalized at one of seven hospitals in the province of Ontario in Canada from 2015 to 2020

L-carnitine group (before operation) (L-carnitine were given before operation)