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Studies have shown that methionine-enriched diets or acute methionine loads cause homocysteine to be exported from cells, leading to increased plasma homocysteine levels (Ueland and Refsum, 1989)

Toyokuni S, Okamoto K, Yodoi J, et al

Resistance when drawing or injecting If the solution seems thicker than usual, requires more pressure to draw into the syringe, or feels different during injection, aggregation may have increased the viscosity

Risk varies by individual and is usually reversible with treatment

Second-generation Instrumentation The foregoing assessment points to the need for relatively inexpensive turnkey instrumentation specifically designed for affinity tag protein purification