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Dual receptor activation (GHRH-R + GHS-R1a) produces synergistic GH pulses that exceed either compound alone while still preserving pulsatility

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A distinct tissue-repair cluster shared this profile but also upregulated genes involved in the remodeling of extracellular matrix ( Fbln2 , Col6a2 , Adamts1 , Adamts5 (Loreti and Sacco, 2022

On the other hand, analysis of a Hey1-eGFP transgenic reporter mouse line shows more prominent GFP signal in the peri-arterial, SOX17 + side of the villus capillary network and in large mesenteric arteries, reflecting the known role of Notch signaling in arterial specification (Fig

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