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SAM's many roles: SAM is the primary methyl donor, used in DNA/RNA methylation, protein modification, and synthesis of neurotransmitters and hormones

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The signal was developed with the chromogen 3,3'-diaminobenzidine in a Bond-Max automatic slide stainer (Leica Biosystems Melbourne Pty Ltd., Melbourne, Australia)

Additionally, researchers studying complex conditions like PCOS encounter inconsistent bioactivity across models and limited assay reliability