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GLP-1RAs counteract diabetic hyperglycemia and dyslipidemia GLP-1RAs effectively treat hyperglycemia and decrease glycated hemoglobin (HbA1c) levels in individuals with T2DM

3) is another TLR family member upregulated in MASLD and lipopolysaccharide (LPS), ROS, HMGB1 and various damage-associated molecular patterns can bind to TLR4 in KCs to promote TNF-, IL-1, IL-6 and interferon- (IFN-) production of various pro-inflammatory cytokines, thereby contributing to hepatic inflammation and the progression of MASLD (54)

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