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Since ammonium is the only nitrogen source in MM medium, the gdh3 / gdh3 mutant may rely on Gdh2 to incorporate ammonium into glutamate

Clinical decision-making has become further complicated by the emerging significance of TDLNs for tumor antigen presentation (30), T cell priming (3133), immunotherapy response (3436), cancer vaccines (3739) and CAR-T therapy (4042), underscoring the need to consider the implications of LN removal on immunotherapy

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1C), warranting further investigation