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If you smoke or use tobacco products and have noticed new or changing pigmentation on your tongue, this is worth mentioning to your clinician as part of the overall evaluation

Additional tests may include liver function tests (ALT, AST, ALP, bilirubin, albumin) and renal function tests

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She explained that this loss of muscle can lead to a lower metabolic rate, sunken skin and even osteoporosis in severe cases

[DOI] [PMC free article] [PubMed] [Google Scholar] 78.Petukhova L, Duvic M, Hordinsky M, Norris D, Price V, Shimomura Y, Kim H, Singh P, Lee A, Chen WV, Meyer KC, Paus R, Jahoda CA, Amos CI, Gregersen PK, Christiano AM