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The inhibition of chemerin increases intracellular PUFA levels and decreases MUFA levels, leading to impaired mitochondrial respiratory chain function and CoQ10 and CIV down-regulation, resulting in more ROS generation and the induction of iron-mediated cell death (85)

Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimers disease transgenic mice

Ischaemia can also be caused by the rupture of intracranial vessels, resulting in intracerebral haemorrhage

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