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Systemic actions: They are both found in several tissues, as well as in circulation, where they modulate metabolism, oxidative stress, cell survival, and inflammation

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However, from 1 January 2026, markers of tirzepatide (Mounjaro/Zepbound) were added to WADA's Monitoring Program

Consequently, once-daily subcutaneous administration of liraglutide 3.0 mg was developed for the treatment of obesity [21] and once-weekly subcutaneous administration of semaglutide 2.4 mg is currently being investigated in phase III trials for this indication [22]

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