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Take home message At standard doses, Mounjaro produces greater average weight loss than Wegovy (20.2% vs 13.7% in clinical trials)

Direct infection of pituitary or adrenal tissue, direct damage to the adrenal gland or pituitary caused by the immune system due to antibody production and/or cell damage, and inhibition of the HPA axis induced by inflammatory cytokines (functional hypopituarism) (36)

Co-corresponding author and co-first author Fabio Hecht, PhD, and co-first author Marco Zocchi, PhD, led the study in the Harris lab in the Department of Biomedical Genetics

(2) fails to meet both the quality performance standard and alternative quality performance standard for any 3 performance years within an agreement period, regardless of whether the years are in consecutive order

Simon A, Bontemps Y, Hornebeck W, Maquart FX