Recent studies, including those carried out in the Kidney Precision Medicine Project, have shown, using single-cell RNA-Seq kidney research biopsies, the expression of the GLP-1 receptor in juxtaglomerular cells, endothelial cells, and, to a lesser extent, monocytes ( In CKD there is increased interest in the relative roles of local intrarenal macrophages versus infiltrating macrophages from the systemic circulation in promoting renal injury
If you struggle significantly with one GLP-1 medication, you may tolerate a different one better
Many researchers incorporate it alongside other peptides for complementary effects
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00:19:35 Steve Small: Yeah, Id agree with that even with this association