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Reportedly, GLP-1R is expressed on monocytes [119]

Epidemiology of Type 2 Diabetes Global Burden of Disease and Forecasted Trends

Efficacy and Safety of Lixisenatide Once-Daily Morning or Evening Injections in Type 2 Diabetes Inadequately Controlled on Metformin (GetGoal-M)

In addition to the US FDA approved GLP-1RAs, there are GLP1/glucagon dual agonists (Cotadutide, BI 456906), GIP/GLP1 dual agonists (Tirzepatide, GIP/GLP peptide I and II), GIP/GLP1/glucagon tri-agonists (HM15211, GGG tri-agonist) and GLP1R agonists (Efpeglenatide, Rybelsus) currently in phase 1- III clinical trials for T2D, obesity, and NASH (MASH) treatments (12)

How to Get Prescribed GLP-1 for Weight Management Getting prescribed a GLP-1 medication depends on your health status and whether you meet certain eligibility requirements