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Since being approved for weight loss almost two years ago, semaglutide has been hailed as a "game-changer" Semaglutide originated as a diabetes medication but was FDA-approved to treat obesity in 2021

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The promising effects observed in vitro often require sophisticated formulations (e.g., with piperine, nanoparticles) to be partially translated in humans, raising questions about the efficacy of simple dietary intake or standard extracts (50)

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