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GABA Homeostasis Under Depression GABAergic system is involved in most psychiatric disorders including major depressive disorder (131), schizophrenia (132), bipolar disorder (133) and autism (134)

Lentz et al, 1996) investigations that suggest a causal relationship between elevated homocysteine levels and vascular spasm and thrombosis and with cross-sectional studies, which suggest that elevated homocysteine levels contributed to acute fatal thromboembolic events (Alfthan et al, 1997

Maintaining adequate B12 levels ensures healthy red blood cell production and prevents this form of anaemia

These changes include, among others, nitration (tyrosine or tryptophan residues) or S -nitrosation, mainly of proteins or peptides with -SH groups (Mller et al

This leads to more oxidative stress and age-related diseases