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It is a designation used primarily by the FDA (Food and Drug Administration) for products, often in vitro diagnostic (IVD) components like reagents or instruments, that are in the laboratory research phase of development and are not intended for clinical diagnostic use

Based on the published literature for its individual components, Wolverine Blend is relevant to research involving tendon and ligament biology, skeletal muscle, connective tissue repair, angiogenesis, wound healing, musculoskeletal research and regenerative biology

Cancer Res 2005

They typically contain ingredients like L-citrulline, L-arginine, watermelon extract, or beetroot powder all known to support healthy blood flow and vascular health

For example, ERs are very important in vascular endothelial cells, which line blood vessels