or rapid heartbeat. Optic nerve damage in people with hereditary eye disorders such as Lebers optic neuropathy (high-dose B12 may precipitate optic atrophy). Peripheral neuropathy with prolonged high-dose pyridoxine (B6). Liver toxicity or significant flushing with large niacinamide doses.Who should not use Lipo-B: Do not use Lipo-B if you are allergic to any B-vitamin or other component of the formulation. Do not use Lipo-B if you have a history of Lebers optic neuropathy. Do not use Lipo-B if you have severe liver disease or active peptic ulcer disease without provider clearance. Do not use Lipo-B if you are pregnant or breastfeeding unless your provider determines the benefits outweigh the risks.Before starting Lipo-B, tell your healthcare provider if you have any other medical conditions, including if you: Have or have had liver or kidney problems. Have cardiovascular disease, elevated homocysteine, or gout. Have peripheral neuropathy or sensory disorders. Are taking any prescription medications, over-the-counter medicines, vitamins, or herbal supplements

Alternative reconstitution for 5mg vial: Adding 2.5ml of bacteriostatic water creates a concentration of 2mg/ml (2000mcg/ml)
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These infections can come in many forms from candida in the gut, to Epstein Barr, or even Lyme disease
The evidence is promising, and day-to-day follow-through still matters