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GHS-R1a antagonists have been shown to suppress alcohol consumption using several different paradigms (two-bottle choice, limited access, intermittent access and fixed ratio operant self-administration) (Jerlhag et al., 2009

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there are little data on the safety of continued use of these agents in patients who develop an infection while on therapy, although anecdotal evidence suggests that they can safely be restarted in many cases after the infection has resolved

This method is sometimes used for deep tissue injuries or when targeting specific muscle groups