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Metformin indirectly regulates hepatic gluconeogenesis by controlling glycerol delivery to the liver through white adipose tissue (WAT) lipolysis

Fasting, a conserved determinant of aging, improves disease outcomes and extends lifespan, yet the relative contributions of lipid catabolism versus its attenuation to fasting-induced longevity remain unresolved

Chapter 4 - neural ECM molecules in axonal and synaptic homeostatic plasticity, in Progress in brain research : Brain extracellular matrix in health and disease

Over the last 2 decades, IGF-1 has been discovered providing a positive scientific basis for its use in treating tendon disorders

Biological assays, chemical proteomics and co-crystallization studies confirmed target engagement, with enhanced binding of ether derivatives to HpTpx