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C.YoungJ.et al (2001)

15 Current evidence supports the role of cGSTs in facilitating multidrug resistance across different types of tumors

Fig.3 Proportion of patients achieving MASH resolution without worsening of fibrosis with tirzepatide [6] While GLP-1 RAs are proving effective in treating MASH, their lack of direct action on liver tissue could limit their effectiveness in patients with advanced liver fibrosis or cirrhosis