Beyond hormonal changes, several interconnected factors may contribute to perimenopausal weight gain: Metabolic slowdown : Basal metabolic rate naturally decreases with age, meaning the body burns fewer calories at rest Muscle mass loss : Sarcopenia (age-related muscle loss) accelerates during perimenopause, further reducing metabolic rate Sleep disruption : Night sweats and insomnia, common perimenopausal symptoms, interfere with hormones regulating appetite and glucose metabolism Mood changes : Anxiety, depression, and stress during this transition may lead to emotional eating patterns Reduced physical activity : Fatigue, joint pain, and other symptoms may decrease exercise tolerance Research suggests women may gain weight gradually during perimenopause, though individual experiences vary considerably
If hair loss is severe or accompanied by other symptoms like extreme fatigue, thyroid function should be evaluated
However, these are often less pronounced with microdosing compared to standard dosing regimens
A Smarter Way Forward I founded Aurelia because women deserve more than algorithms and templates
Data are estimated mean (CI) changes from the estimated baseline value in UACR, analysed using a mixed model for repeated measurements
