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The Ozempic label lists only two contraindications: a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2, and serious hypersensitivity to semaglutide or its excipients

The parallel to physical rehabilitation after stroke is direct: the peptide creates biological readiness for improvement, but active engagement is needed to direct that improvement toward meaningful functional gains

Valentino A, Calarco A, Di Salle A, Finicelli M, Crispi S, Calogero RA, et al

For understanding the stack this means: the order and the joint presence of both signals is mechanistically relevant, not just the sum of two individual doses